Mohsen Adeli
Lorestan University, Iran
Title: Synthesis of Well-Defined 2D Nanomaterials to Study the Mechanism of Graphene- Pathogen Interactions
Biography
Biography: Mohsen Adeli
Abstract
Understanding the mechanism of interactions between 2D nanomaterials and pathogens is vital to develop and control their antimicrobial properties1-3. This is possible when the system is well-defined. In this work, a stimuli responsive
graphene derivative with defined structure and properties is designed and synthesized and the mechanism of its interactions with E.coli is investigated. Polyethyleneglycol-block-(poly-N-isopropylacrylamide) copolymer (PEG-b-PNIPAM) with the triazine joint point was attached to the surface of graphene by [2+1] cycloaddition reaction and a photothermo responsive nanomaterial was obtained. It was found that hydrophobic interactions is one of the most important driving forces in the graphene-E.coli interface. Transformation of the functionalized graphene sheets from a hydrophilic to hydrophobic state by photo- or thermos- stimuli factors influenced their interactions with the bacteria membrane, dramatically. This study shows that interactions between graphene and pathogens could be controlled by manipulation of the hydrophobicity of their surface.